Clinical evaluation and comparison of the healing effects of “Ak em” cream and “Levomekol” ointment on burn wound

Professor Taganmyrat Hojageldiyev1, MD Yusup  Ishangulyyev2, Mr Yklym Bolmammedov1

1State Medical University of Turkmenistan, Ashgabat, Turkmenistan, 2Multifield Hospital of Ahal Velayat, Buzmeyin, Turkmenistan


Background. Previously conducted experimental studies demonstrated that Peganum harmala, cotton seed oil, and apricot gum based natural cream “Ak em” accelerates wound healing and reduces the microbial burden of wounds in animals (T. Hojageldiyev et al. 2018).

Objective. In the present study, we investigated the efficacy of topical “Ak em” cream and “Levomekol” ointment for the treatment of burn wounds in patients.

Materials and methods. In this clinical trial, 34 patients with second-degree burn referring to the burn ward of Multifield Hospital of Ahal Velayat were divided into two equal groups. The burns were locally applied with “Ak em” cream in group 1, “Levomekol” ointment in group 2. Healing was assessed by the rate of wound healing and the planimetric method.

Results. “Ak em” cream significantly increased the rate of wound contraction when compared to “Levomekol” ointment. In 15 days burn wounds of all patients in group 1 were totally healed, but it takes 30 days in group 2. The percentage of wound contraction was significantly higher in group 1 as compared to group 2 (p<0.05).

Conclusion. The greatest rate and percentage of healing was in the “Ak em” cream, so the application of herbal cream as a suitable substitute for the healing of burn wound is recommended.


24-year-old medical sciences graduate, currently in the first year of Internal Medicine Residency. Background includes winner of International Olympiads, hands-on experience in scientific and medical researches as being Research Assistant in Scientific Research Department for more than 3 years and Active member of Young Scientists Society of Academy of Sciences of Turkmenistan and participated several international scientific conferences.

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